Huntington’s Disease

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ISBN: 9780323956727
Published: 2024
Publisher: Academic Press
Language: English
Format: Paperback / softback
Format: 9×5.94

Description

<p>Huntington's disease (HD) is one of the most common dominantly inherited neurodegenerative disorders, characterized by a clinical triad of movement disorder, cognitive deficits, and psychiatric symptoms. <i>Huntington’s Disease: Pathogenic Mechanisms and Implications for Therapeutics</i> reviews the most up-do-date content on HD pathogenic mechanisms and cutting-edge thinking on therapeutic strategies for HD. Chapters explore areas that include the clinical features and genetic studies of HD, the cellular and molecular biology of normal huntingtin, a range of HD models, the diverse pathogenic mechanisms linked to mutant huntingtin, new approaches to HD pathogenesis, as well as emerging preclinical therapeutic approaches and clinical programs in the field.</p>

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